HPLC and GC-MS Analysis
PetroLabs currently offers HPLC and GC-MS analysis as experimental support for our Modified Ames Test and IP 346 results, but we also offer standard EPA testing services upon request. In recent months we have also begun to explore the combination of semi-preparative HPLC and GC-MS as a means of exploring composition-activity relationships for refinery streams, and in support of client efforts to fine-tune refinery extraction or hydrotreating operations.
Our Services
MODIFIED AMES TEST
The Modified Ames Test was developed by Mobil Oil Corporation scientists in 1983 as a screening assay for the dermal carcinogenicity of petroleum oils. The test has become the most widely used short-term biological assay in the petroleum industry. It was adopted in 1995 as ASTM Standard Method E 1687.
IP346/80 TESTING
The Method IP 346 was developed by Shell scientists as a chemical screening assay for dermal carcinogenicity. Like the Modified Ames Test, it relies on the fact that the principal carcinogens in oils are PAC, and that the biologically active members of the class are readily extractable into dimethyl sulfoxide (DMSO).
CONSULTING
In partnership with Greener Tox Solutions, Biodegradation Studies, and Microtox, Petrolabs has the expertise to provide consulting services in the arena of mutagenicity and Aquatic Toxicology Assays. Let us put our expertise to work for you designing custom solutions to meet your organization’s specific needs.